Recent breakthroughs with mRNA-based vaccines highlight the potential of lipid-based particles as powerful and versatile delivery vectors for vaccines and gene therapies. Used to measure particle size, stability, zeta potential and particle concentration, light scattering techniques are used extensively in the characterization of lipid nanoparticle and liposome research.
The Zetasizer range of light scattering instruments provides high quality, stability-indicating data for drug molecules and their formulations. Delivering data in a short time frame, the Zetasizer allows you to implement this technique throughout the development pipeline.
This webinar explores the challenges and opportunities drug and vaccine developers are currently facing and explains how the Zetasizer can be used to address these and to optimize your formulations.
発表者
- Mike Kaszuba - Technical Support Manager, Malvern Panalytical
詳細
Who should attend?
- Scientists and project Leaders working on the design, process and formulation development of lipid nanoparticles and liposomes for drug and vaccine delivery.
What will you learn?
- Learn how and why size, zeta potential and particle concentration can be used as critical quality attributes in lipid nanoparticle and liposome formulations
- Explore how DLS can be used to optimize lipid-based formulations and process conditions, such as monitoring stability, understanding surface modification, and developing formulations
- Understand the significance of Non-invasive backscatter (NIBS) optics for reliable measurements of concentrated, turbid samples without the need for dilution