| 00:00:00 | Sieve less, see more! In-line particle sizing improves process control |
| 00:00:58 | Overview |
| 00:01:32 | Understand the relevance.. |
| 00:02:05 | Heywood & Scarlett |
| 00:03:55 | Properties influenced by particle size |
| 00:04:16 | Basic principles |
| 00:05:23 | Basic principlesEquivalent sphere - volume/mass |
| 00:06:21 | Sieves |
| 00:06:51 | Sieves |
| 00:07:56 | Sieving - a comparison problem |
| 00:08:07 | Sieving |
| 00:08:31 | These particles will also pass the screen |
| 00:09:56 | Spatial Filter VelocimetryChord Length Distribution Analysis |
| 00:09:56 | PARSUM Probe |
| 00:10:26 | Parsum Probe |
| 00:11:24 | Extended Spatial Filter Technique |
| 00:12:01 | SFT – Dynamic Behavior of the Measurement |
| 00:13:15 | Coincidence of particles |
| 00:14:05 | Visualization in fractions |
| 00:14:30 | Software |
| 00:14:55 | Comparability of measuring methods |
| 00:15:40 | Continuous Granulation Process Monitoring |
| 00:16:17 | Continuous Granulation Process Monitoring |
| 00:16:46 | Monitoring a screening process |
| 00:18:06 | Fluidized Bed - Top Spray Granulation |
| 00:18:41 | Continuous granulation |
| 00:19:33 | High Shear Granulation |
| 00:19:47 | High Shear Granulation in pictures |
| 00:21:20 | Methods used to evaluate granulate |
| 00:22:05 | High Shear Granulation |
| 00:22:51 | Screenshot of a typical batch |
| 00:23:24 | Reproducibility and Scalability |
| 00:24:20 | Tablet dissolution |
| 00:24:31 | Summary |
| 00:25:30 | Thank you for your attention |
| 00:25:42 | Contact us |
Sieve analysis is one of the oldest techniques for evaluating granule size and even today is employed widely in quality control across variety of industries including pharmaceutics, despite being gradually replaced by more modern methods such as laser diffraction. Reliance on sieving as the primary method for process control often results in a heavy workload for plant operators, poor precision and significant time lags between sampling and analysis.
This presentation will discuss the use of in-line particle size analyzers as an alternative to manual sampling and as means of improving process understanding and control, and product quality.
This presentation will discuss the use of in-line particle size analyzers as an alternative to manual sampling and as means of improving process understanding and control, and product quality.