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Explore our Vector Analytics webinar hub, where you’ll find insights, tips and advice from biophysical characterization and technology experts.
Optimize lipid nanoparticle formulation, manufacturing, and quality control with the right analytical tools
Lipid nanoparticles are small spherical vesicles formed of a mixture of ionizable cationic lipids, helper lipids (such as DSPC and cholesterol), and PEGylated lipids.
These tiny structures offer immense benefits as a drug delivery system, including:
Lipid nanoparticles have a range of medical applications, the most prominent being delivery of DNA and RNA payloads for prophylactic or therapeutic vaccines, in addition to other therapies.
To better measure these attributes and support confident formulation decisions, developers and manufacturers need a suite of advanced, orthogonal biophysical characterization methods, including:
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Formulating lipid nanoparticle products to optimize their stability and therapeutic efficacy is no easy feat since formulation depends not only on the formulation components but also on the formulation process.
Selecting the right formulation strategy demands deep and accurate insights into the attributes of your lipid nanoparticle samples, including:
Explore our Vector Analytics webinar hub, where you’ll find insights, tips and advice from biophysical characterization and technology experts.
Malvern Panalytical offers the full range of tools and expertise to confidently characterize lipid nanoparticles for better formulation decision-making and faster program progression:
Want to find out more about which tools to use, and when, in your lipid nanoparticle characterization? Download our free eBook
Manufacturing consistently high-quality lipid nanoparticle products poses numerous challenges. LNP developers must understand the impact of (and be able to optimize) manufacturing process parameters and be able to rapidly conduct batch-to-batch consistency and stability studies.
What’s more, personalized medicines (which are the focus of many LNP therapies) can make QC testing and analysis much more demanding.
To succeed, LNP developers need deep, rapid, and accurate insights into the attributes of their LNP formulation, including:
Malvern Panalytical provides the full range of analytical tools and expertise you need to confidently characterize your lipid nanoparticles to optimize manufacturing and drive quality:
Discover what your peers are asking about lipid nanoparticle characterization
With decades of experience in the field of pharmaceuticals, Malvern Panalytical has built a reputation for excellence. Our portfolio of innovative analytical technologies is designed to meet the complex needs of pharmaceutical and biopharmaceutical research, development, and manufacturing.
We are committed to continuous innovation and maintaining the highest standards of quality. By investing in research and development, Malvern Panalytical consistently introduces cutting-edge solutions that address the evolving challenges in pharmaceuticals, including dissolution testing.
To find out more about how our solutions can enhance your lipid nanoparticle formulation development and manufacturing processes, contact us today. Our experts are ready to provide you with detailed information, demonstrations, and tailored solutions to meet your needs.