Using XRF to maximize the efficiency of drug purification processes

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Are you tasked with scaling up a drug substance and ensuring the elemental purity of your products and process streams? Looking to streamline purification and catalyst scavenging with fewer process steps? Typically, the go-to tool to check for elemental impurities in pharmaceutical samples is one of the plasma-based techniques such as ICP-OES or ICP-MS. These techniques are accurate, but they are also slow to deliver results and costly to run.

There is a faster, easier and more cost-effective alternative: energy-dispersive X-ray fluorescence (EDXRF). It’s simpler to deploy and gives you results in minutes, not hours.

Join our webinar to learn how pharmaceutical manufacturing teams at Gilead Sciences use XRF to streamline elemental analysis. Discover real-life case studies and learn how using EDXRF can help you to:

  • Better understand your reaction mixture purification strategies
  • Troubleshoot unexpected outcomes by detecting trace contaminants
  • Avoid long wait times and complicated calculations of much more complex elemental analysis approaches, such as ICP-OES
  • Free up resources by providing XRF training to as many researchers as needed independent of their prior knowledge of this technology

We’ll also cover:

  • Basics of EDXRF and its application in the pharmaceutical industry
  • X-ray safety and why you should not worry about working with an XRF instrument
  • Accessibility and ease-of use of Malvern Panalytical EDXRF instruments

演講者

  • Dr Sean Liew, Senior Research Scientist I at Gilead Sciences
    Sean is from Edmonton, Alberta, Canada and holds a PhD in synthetic organic chemistry from the University of Toronto. Sean has been a process chemist at Gilead Alberta for nearly 8 years and is responsible for process optimization and scale-up manufacturing of drug substances.

  • Dr Natalia Dadivanyan, Segment Marketing Manager, Small Molecule Pharmaceuticals at Malvern Panalytical

  • Lieven Kempenaers - Product Manager, Malvern Panalytical

更多資訊

Who should attend? 

  • Those interested in the analysis of elemental impurities in pharmaceutical products and ingredients
  • Those interested in drug safety and toxicology with regard to elemental impurities
  • Those considering XRF as an alternative to ICP or ICP-MS for the detection and quantitation of elemental impurities in drug products

What will you learn? 

  • Understand the basics of EDXRF and its application in the pharmaceutical industry
  • Learn about X-ray safety – spoiler alert: you should not worry about working with an XRF instrument
  • Learn how using EDXRF can help you to better understand your reaction mixture purification strategies
  • Understand how to troubleshoot unexpected outcomes by detecting trace contaminants
  • and more....