Key Considerations for characterizing LNPs

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Lipid Nanoparticles (LNPs) are the most common vector being used in the development of nucleic acid-based gene therapies and vaccines.

This webinar highlights the key considerations for LNP development, including LNP structure, formulation parameters, and the function of each lipid component.

We will discuss the common and advanced analytics used to characterize LNPs, what physicochemical properties are measured, and how these properties relate to LNP critical quality attributes. Finally, we will review several key publications that demonstrate the relationship between LNP physicochemical properties and functional assays to determine immunogenicity and long term stability.

This presentation is intended for any scientist involved in the development of LNP-based therapeutics, including LNP formulation scientists, LNP analytical development scientists, and LNP discovery scientists.

Vaccines And Nucleic Acid-Based Therapies Webinar Series

In this three-part webinar series, we will explore several areas critical to LNP vaccine and gene therapy development. 

Want to know more? 

Register for free for any sessions in our webinar series - and keep an eye out for the recordings afterward too!

  • Key Considerations for Characterizing LNPs (this webinar)
  • Understanding and Controlling stability of LNPs using DLS and NTA - April 18, 2024 - Find out more
  • The Role of Charge in the Formulation of LNPs - May 2, 2024 - Find out more

발표자

  • Jonathan Mehtala, PhD: Team leader – Biologics Development, Malvern Panalytical

자세한 내용

Who should attend? 

  • Any scientist involved in the development of LNP-based therapeutics, including LNP formulation scientists, LNP analytical development scientists, and LNP discovery scientists.

What will you learn? 

  • Common and advanced analytics used to characterize LNPs
  • What physicochemical properties are measured and how these properties relate to LNP critical quality attributes
  • We'll review several key publications that demonstrate the relationship between LNP physicochemical properties and functional assays to determine immunogenicity and long term stability