Zetasizer Ultra Masterclass 1: Why do I see large %CV in my particle concentration measurements?

In this short webinar we will be looking more closely at why %CV of particle concentration measurements vary more when there are aggregates present in the sample.

We will look at how the calculation of concentration from a multi-angle dynamic light scattering (MADLS) measurement in a Zetasizer Ultra is performed and identify the factors that may affect the repeatability and accuracy of these measurements. We will also outline some general guidelines for best practice for these types of measurements.

In this short webinar, we will use adeno-associated virus (AAV) samples to look more closely at why the %cv of particle concentration measurements varies more when there are aggregates present in the samples.

We will look at how the calculation of concentration from a multi-angle dynamic light scattering (MADLS) measurement on a Zetasizer Ultra is performed, and identify the factors that may affect the repeatability and accuracy of these measurements. We will also outline some general guidelines for best practice for these types of measurements.

• Who should attend? 

- Scientist working with characterization and development of viral vectors for gene therapy and vaccines. 

• What will you learn?

- How the multi angle dynamic light scattering technique works for %cv and factors that affect the outcome of your analysis.