| 00:00:00 | PST and BDAS - an acronym approach to laser diffraction method development |
| 00:01:55 | Abstract |
| 00:02:29 | Obligatory Opening Quotation (O2Q) |
| 00:03:53 | Shameless plug |
| 00:04:10 | …as well as Malvern application notes |
| 00:04:37 | Developing an SOP (Standard Operating Procedure) |
| 00:05:34 | The infamous 4Q’s |
| 00:08:05 | How do we know whether there are agglomerates in the system? |
| 00:08:59 | Harold Heywood |
| 00:09:27 | Design of Experiment |
| 00:10:18 | Specification |
| 00:11:25 | Why? |
| 00:12:00 | Why? |
| 00:12:36 | Why? |
| 00:13:27 | The 3 R’s and 3 M’s of SOP’s |
| 00:14:34 | 3R’s & 3M’s in particle sizing |
| 00:15:01 | The golfing analogy |
| 00:15:26 | Measures/markers of precision |
| 00:16:26 | 3 R’s sorted out in method development |
| 00:18:30 | General rules – “large” sizes |
| 00:19:23 | General rules – “small” sizes |
| 00:20:02 | Dispersion |
| 00:20:59 | SOP development - general |
| 00:21:59 | Dry and wet |
| 00:23:52 | Dry and wet |
| 00:25:04 | Dry dispersion - Basics |
| 00:26:26 | Venturi type |
| 00:26:44 | Method development - dry |
| 00:27:42 | Method development - dry |
| 00:29:04 | ISO13320: 2009 Section 6.2.3.2 Dispersion in gas |
| 00:29:47 | Dry - theoretical and practical plots |
| 00:30:19 | Dry - theoretical and practical plots |
| 00:30:46 | Dry - example |
| 00:31:49 | Dry - example |
| 00:32:25 | Dry analysis |
| 00:33:17 | Dry – example of attrition |
| 00:34:19 | How to look for segregation in a powder |
| 00:34:35 | Obscuration control |
| 00:35:53 | Obscuration control |
| 00:36:53 | Controlling the feed rate (mass flow) |
| 00:37:43 | Issues to consider with a dry SOP |
| 00:38:43 | Is the dispersion correct? |
| 00:39:18 | Stages in making a stable dispersion |
| 00:40:01 | Method development - wet |
| 00:41:30 | Wet - theoretical and practical plots |
| 00:42:28 | Wetting |
| 00:43:56 | Wetting |
| 00:44:29 | Wetting |
| 00:44:55 | Dispersants for Nanometer Size Particles |
| 00:45:22 | Stabilization |
| 00:46:51 | Ceria - CeO2 |
| 00:47:55 | Titanium dioxide |
| 00:48:32 | Indications that there is a stability issue |
| 00:49:03 | Stability studies with Zetasizer plus titrator |
| 00:50:39 | Method development - wet |
| 00:51:02 | Wet – dry comparison |
| 00:51:21 | Wet – dry comparison |
| 00:51:36 | Powder Coating - Size/Pressure |
| 00:52:22 | Comparison - wet/dry |
| 00:52:43 | Comparison between wet and dry |
| 00:52:54 | In MS2000 & MS3000 can do this directly |
| 00:53:08 | Sample Name – use for any change |
| 00:53:20 | Check on method (development) |
| 00:53:37 | Points to note |
| 00:53:58 | So what D pressure to measure at? |
| 00:54:28 | Overlap at what pressure? |
| 00:54:45 | Try another material |
| 00:54:56 | Toner PST |
| 00:55:06 | Wet - dry comparison |
| 00:55:39 | General indicators in the PST & BDAS plots |
| 00:56:00 | Method development: microsilica |
| 00:56:22 | Microsilica |
| 00:56:38 | ISO13320: 2009 |
| 00:57:08 | ISO13320: 2009 |
| 00:57:25 | Setting up the SOP |
| 00:57:46 | What do I need to think about and define before I even attempt a particle size measurement? |
| 00:57:57 | Thank you for viewing and listening |
| 00:58:10 | Question & Answers |
| 01:04:43 | Thank you for your interest |
Exploring the effect of increasing energy on a particulate system is the general approach to method development in laser diffraction. In this manner agglomerates can be distinguished from primary particles. Energy is applied by altering the differential pressure (P) in a dry measurement in the pressure-size titration approach and in the wet systems by application of ultrasound energy in the before, during, and after sonication (BDAS) approach. This seminar will illustrate the methodologies by means of appropriate examples and reference to ISO 13320: 2009
演講者
Alan Rawle Ph.D - Expert in Laser Diffraction