| 00:00:00 | Optimization and Characterization of Nanomaterials for Drug Delivery Applications: Liposomes |
| 00:02:14 | Optimization and Characterization of Nanomaterials for Drug Delivery Applications: Liposomes |
| 00:02:23 | Contents |
| 00:02:53 | Contents |
| 00:03:00 | What are Liposomes? |
| 00:03:53 | Liposomes for Drug Delivery |
| 00:05:49 | Contents |
| 00:06:00 | Untitled |
| 00:06:49 | Slide9-Particles are Visualised Directly, in Real Time |
| 00:06:49 | Slide10-NTA: Principle of Measurement |
| 00:06:49 | Slide11-Particle Sizing in action - Software Analysis |
| 00:06:49 | Untitled |
| 00:08:35 | Contents |
| 00:08:41 | Zetasizer Nano Series |
| 00:12:04 | Dynamic Light Scattering |
| 00:14:14 | Zeta Potential |
| 00:17:25 | Electrophoretic Light Scattering |
| 00:19:46 | Size and Concentration Limits* |
| 00:22:02 | Contents |
| 00:22:24 | Slide20-What do liposomes “look” like with NTA? |
| 00:22:24 | Untitled |
| 00:23:41 | Untitled |
| 00:24:47 | Slide23-Foslip® in PBS Measured by NTA |
| 00:24:47 | Slide24-Serum Background Measured by NTA |
| 00:24:47 | Slide25-Serum Destruction of Foslip® measured by NTA |
| 00:24:47 | Untitled |
| 00:25:47 | Untitled |
| 00:27:29 | Contents |
| 00:27:38 | Liposome Composition: Anionic |
| 00:28:06 | Liposome Characterisation: Anionic |
| 00:28:33 | Liposome Composition: Cationic |
| 00:28:49 | Liposome Characterisation: Cationic |
| 00:29:06 | Cationic Liposomes in Gene Therapy |
| 00:29:40 | Cationic Liposomes in Gene Therapy |
| 00:31:57 | Coated Liposomes (Steric Stabilisation) |
| 00:33:04 | PEG-Coated Liposomes |
| 00:36:15 | Conclusions |
| 00:36:57 | Further Information |
| 00:37:33 | Many thanks for your attentionAny questions? |
| 00:52:59 | Contact Information |
The physical characterization of liposomes is of great importance in understanding their suitability for a range of applications. Knowledge of the size, concentration and zeta potential of a liposome preparation can help to predict its fate in vivo. Association of charged liposomes with oppositely charged molecules can be monitored by measuring the zeta potential of the resulting complex. This webinar will discuss the suitability of the Zetasizer Nano and of Nanoparticle Tracking Analysis (NTA) for the characterisation of liposomes with reference to a number of application studies.