The properties of polymeric excipients can directly affect the clinical efficacy, safety, and quality of a finished pharmaceutical product and are routinely identified as critical quality attributes (CQAs). This article looks at how gel permeation/size exclusion chromatography (GPC/SEC) can be applied to measure characteristics such as molecular weight, distribution, structure, and degree of branching.
The properties of polymeric excipients can directly affect the clinical efficacy, safety, and quality of a finished pharmaceutical product and are routinely identified as critical quality attributes (CQAs). This article looks at how gel permeation/size exclusion chromatography (GPC/SEC) can be applied to measure characteristics such as molecular weight, distribution, structure, and degree of branching.
