| 00:00:00 | Welcome |
| 00:00:55 | Particle Sizing Masterclass 4:Setting Specifications |
| 00:01:12 | Particle Sizing Masterclass |
| 00:02:19 | Overview |
| 00:03:30 | What is a specification |
| 00:03:41 | What is a specification? |
| 00:04:41 | What should specifications be based on? |
| 00:07:14 | How should specifications be justified? |
| 00:08:13 | Understanding particle size results: Equivalent spheres |
| 00:10:04 | Understanding particle size results: Distribution type |
| 00:12:17 | Particle size distribution statistics: Median and Mode |
| 00:12:52 | PSD Statistics: Median and Mode |
| 00:13:52 | PSD Statistics: Percentiles |
| 00:15:25 | PSD Statistics: Mean particle sizes |
| 00:16:50 | PSD Statistics: Volume weighted mean |
| 00:18:15 | PSD Statistics: Surface area weighted mean |
| 00:19:41 | Particle size distribution statistics: Summary |
| 00:20:47 | Choosing the right parameter to follow the process |
| 00:21:21 | Choosing the right parameter to follow the process |
| 00:22:48 | Measurement precision |
| 00:23:13 | Definitions of measurement precision |
| 00:25:02 | What factors affect measurement precision? |
| 00:25:51 | How many particles do I need to measure? |
| 00:27:15 | How much sample do you need to measure? |
| 00:27:52 | How much sample do you need to measure? |
| 00:28:36 | Standards for Laser Diffraction & Optical Imaging |
| 00:29:12 | What precision values are reasonable? |
| 00:30:52 | How does measurement precision affect the spec? |
| 00:31:37 | How does measurement precision affect the spec? |
| 00:32:20 | Example |
| 00:32:28 | Factors affecting the tableting process |
| 00:33:23 | Specification example: Tablet formulation |
| 00:34:23 | Specification example: Tablet formulation |
| 00:35:22 | Specification example: Tablet formulation |
| 00:37:06 | Linking measurement data and manufacturing specifications |
| 00:37:34 | Conclusions |
| 00:38:32 | Thank you for your attentionAny questions? |
| 00:45:15 | Contact Information |
In the fourth webinar in the particle sizing masterclass we will look at how to set specifications for particle size measurements. The most important thing when setting a specification is to relate it back to why you need to measure particle size. For example, what aspect of product performance, or what part of the manufacturing process, are you trying to control? In this webinar we will look at a few different reasons for setting particle size specifications and what parameters these specifications should be based on. We will also look in more detail at the range of parameters calculated from the particle size distribution, and how they can be used with appropriate tolerances to provide robust specifications.