Predicting the fate of liposomes
For regular readers of Materials Talks wondering who I am, I recently joined Malvern Instruments as a Social Media Manager. I’ll be running Materials Talks, as well as our other social media profiles, such as Twitter and Linkedin, so you will hear from me from time to time.
In this, my first post for Materials Talks, I want to tell you about a great event that will be of particular interest to those working in drug and biotherapeutics research, development and formulation, from Project Managers to Bench Scientists. Are you interested in learning about two complementary techniques that can help liposome characterization? If so, we would love for you to join us for a webinar hosted by not one, but two of our nanomaterials experts, who will discuss the most common drug delivery system, liposomes.
Liposomes as drug delivery vehicles
Recent applications of liposomes have concentrated on their use as drug delivery vehicles due to the ability of incorporating water-soluble materials in their aqueous volume or oil soluble materials in the lipid bilayer. They can be designed for specific applications through control of the lipid composition or modification of the surface by conjugation of antibodies or peptides.
The fate of intravenously injected liposomes is determined by a number of properties, including size, concentration and zeta potential. Knowledge of these properties can help to predict a liposomes fate in vivo. Association of charged liposomes with oppositely charged molecules can be monitored by measuring the zeta potential of the resulting complex.
Two complementary techniques
Join us for the first webinar combining the considerable expertise of Malvern’s Technical Support Manager, Mike Kaszuba, with that of Nanosight’s Senior Application Scientist, Pauline Carnell, in what is sure to be a match made in heaven. The formidable pair will share their expertise on the application of the Zetasizer Nano and Nanoparticle Tracking Analysis (NTA) in liposome research. They will discuss a number of interesting applications, including an example of understanding stability of liposomes for photodynamic therapy for treating cancer.
Register now on the Malvern website for this fascinating event, taking place on Thursday 23rd January 2014 at 10.30 am EST (3.30 pm GMT). If you can’t make it, you can sign up to receive the recording, which will be posted online a week after the event.
Keep a look out on the website for further nanomaterials webinars taking place later this year.
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