Accelerating method development with SOP Architect
The debut session of our 2024 Mastersizer 3000+ series introduced SOP Architect, an innovative feature designed to simplify and enhance method development for laser diffraction measurements. Presented by Dr. Benjamin Lynch and Mohammed Islam, the webinar offered attendees a comprehensive overview of how this tool can streamline workflows and ensure best practices in particle size analysis.
Key takeaways
- Comprehensive method guidance
SOP Architect simplifies complex processes by providing step-by-step instructions and embedded video tutorials. It helps users choose suitable dispersants, optimize dispersion conditions, and identify potential issues like agglomeration or dissolution. - Automation for efficiency and accuracy
Manual titrations for stirrer speed or sample obscuration can be labor-intensive. SOP Architect automates these tasks, running tests across a range of conditions and recommending optimal settings. This not only saves time but also ensures consistency across users and experiments. - Built-in expertise and best practices
The system incorporates insights from industry experts, offering users real-time advice based on extensive R&D. Whether detecting sample instability or preventing multiple scattering, SOP Architect provides actionable recommendations, ensuring that every method adheres to established best practices.
SOP Architect is more than just a tool; it’s an expert built into the software, guiding users through method development and ensuring best practices at every step.
Mohammed Islam
Why focus on method development?
Particle size analysis is crucial in industries ranging from pharmaceuticals to materials science, as it directly impacts product quality and performance. However, the method development process can be challenging, especially for new users or when transitioning between samples with varying properties. Sampling, dispersion, and measurement setup all require precision to ensure reliable results.
Many users rely on manual processes, which can be time-consuming and prone to error. Additionally, as expertise is often passed down informally, best practices can be lost over time. These issues underscore the importance of tools like SOP Architect, which provide guidance, automation, and consistency.
SOP Architect: Revolutionizing method development
SOP Architect, part of the new Mastersizer 3000+ system, addresses these challenges by integrating expert algorithms, automated workflows, and embedded training resources. Designed for wet dispersion, it guides users through seven key steps, including instrument setup, sampling, dispersion, and method repeatability testing.
This innovative feature ensures that users at all experience levels can develop robust methods efficiently. From novices to seasoned operators, SOP Architect offers tailored support, validating existing procedures and automating time-consuming tasks like stirrer speed and obscuration titrations.
Whether you’re a new user or an experienced operator, SOP Architect automates the tedious tasks, so you can focus on getting the best results.
Dr. Benjamin Lynch
Practical guidance
Developing reliable methods for particle size analysis requires attention to detail, from initial sampling to final measurement. SOP Architect ensures that every step is executed with precision.
Sampling and dispersion
SOP Architect emphasizes the importance of representative sampling and proper dispersion techniques including easy to follow step by step videos in built in the software. Whether using a paste method for dense materials or a slurry method for better control, the system helps users maintain sample integrity and achieve consistent results.
Detecting and resolving sample issues
The system’s stability checks automatically detect potential problems like agglomeration, dissolution, or poor dispersion. When issues arise, SOP Architect suggests tailored remedies, such as altering the pH, using stabilizers, or selecting alternative dispersants.
Optimizing parameters
Through automated titration. SOP Architect determines the ideal stirrer speed and obscuration levels for each sample sonication. For example, it identifies the optimal range to suspend particles without introducing turbulence or multiple scattering effects. This reduces guesswork and ensures precise measurements.
Validation and repeatability
SOP Architect’s repeatability testing ensures that methods are consistent and meet standards like USP 429 and ISO as 13320:2020 here. Over the generic ISO 13320. By verifying settings and results, the system builds user confidence in their procedures.
Next in the series…
The Mastersizer 3000+ masterclass series continued with two more sessions:
- Unlock Precision Insights with Size Sure: Mastersizer Xplorer’s Revolutionary Mode for Rapid and Reliable Sample Characterization
- Elevate Your Analysis with Data Quality Guidance: Mastersizer Xplorer’s Essential Tool for Robust Experimental Results
Stay ahead of the curve by watching these on-demand masterclasses and exploring the full capabilities of the Mastersizer 3000+!
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For more insights on improving your particle size measurements and a demo of the Mastersizer 3000+, contact our experts today.