| 00:00:00 | Welcome |
| 00:00:19 | Mark Pothecary |
| 00:00:25 | Multi-detector UPLC |
| 00:01:38 | Size-exclusion chromatography |
| 00:03:23 | Overview of Multi-detector sec |
| 00:03:34 | Multi-detector SEC |
| 00:05:08 | Refractive index |
| 00:06:05 | UV-Vis Detection |
| 00:07:06 | Static light scattering |
| 00:08:26 | Intrinsic viscosity |
| 00:09:46 | Mark-Houwink plots |
| 00:11:16 | Branching |
| 00:11:56 | The multi-detection pyramid |
| 00:13:08 | Multi-detector SEC summary |
| 00:13:29 | Watersacquity APC |
| 00:16:35 | Waters ACQUITY APC |
| 00:19:34 | Multi-detector UPLCOMNISEC & APC |
| 00:19:43 | Why are we interested in UPLC? |
| 00:21:10 | Challenges involved with Multi-detection UPLC |
| 00:22:18 | Analytical GPC |
| 00:22:56 | Dispersion in UPLC |
| 00:23:36 | Hardware improvements |
| 00:25:58 | Dispersion in UPLC |
| 00:26:58 | Improve sensitivity |
| 00:27:08 | Sensitivity in analytical SEC |
| 00:27:26 | Sensitivity in UPLC |
| 00:28:21 | Improve measurement speed |
| 00:28:29 | Polystyrene Branching |
| 00:29:57 | PLA/PLGA |
| 00:30:07 | Copolymer PLGA 75:25 |
| 00:30:38 | PLA/PLGA |
| 00:31:16 | Drug delivery polymer |
| 00:32:57 | Improve resolution |
| 00:33:18 | Oligomeric resolution |
| 00:34:19 | POlycaprolactone |
| 00:34:24 | PAO |
| 00:36:41 | Multi-detector UPLC |
| 00:37:53 | Thanks for listening |
| 00:38:17 | Contact Information |
Multi-detector GPC/SEC offers superior information about polymers, including absolute molecular weight, size, and structure, when compared with conventional single-detector measurements. At the same time, UPLC offers a step-change in the resolution and speed of polymer separations, using small columns and particle sizes to achieve high plate counts. Previously these two techniques have been incompatible due to band-broadening and dispersion effects that take place as narrow UPLC peaks pass through multiple detector cells.The latest enhancements to Malvern Panalytical's OMNISEC REVEAL detector platform now bring these two class leading technologies together. Combining the information-rich data from multi-detector GPC/SEC with the speed and resolution afforded by UPLC (Water's ACQUITY APC).
This webinar will briefly describe advanced detection and UPLC, and discuss how these two technologies have been brought together. Application examples will be provided showing how this data really can be generated in just a few minutes.
Vortragende
Mark Pothecary studied biochemistry while an undergraduate at the University of Bath before moving to London to obtain his Masters and PhD the William Harvey Research Institute, part of the Queen Mary College between 2002-2006. There he studied the biochemical effects of red wine polyphenols on the production of nitric oxide in blood vessels and the subsequent control of blood pressure.
Mark joined Malvern in 2008 as a product technical specialist for the Zetasizer Nano and Viscotek products concentrating on bioscience SEC applications. He is now the Americas Product Manager for our chromatography products.
Weitere Informationen
Why attend?
Learn about the benefits of coupling Malvern Panlytical's OMNISEC REVEAL multi-dector to Water's ACQUITY APC, such as quicker measurements, reduced solvent and more detailed information about your macromolecules.
Who should attend?
Scientists looking to save time and money by upgrading to multi-detector UPLC, including;
- GPC/SEC users
- UPLC/UHPLC users
- polymer chemists
- biochemists
- Lab managers
- anyone interested in molecular weight and absolute molecular weight or polymer characterization
What will you learn?
The background of multi-detector GPC/SEC and UPLC measurements and how they can be combined to provide more detailed information about your macromolecules in a much shorter time.