Recently, Evotec has successfully harnessed Grating Coupled Interferometry (GCI) technology for fragment screening against G-protein coupled receptors (GPCRs), a notoriously unstable class of proteins. In this case study, Dr. Edoardo Fabini, (Principal Scientist at Evotec) discusses the challenges of studying GPCRs and how WAVEsystem enabled confident measurements under these difficult conditions.
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Recently, Evotec has successfully harnessed Grating Coupled Interferometry (GCI) technology for fragment screening against G-protein coupled receptors (GPCRs), a notoriously unstable class of proteins. In this case study, Dr. Edoardo Fabini, (Principal Scientist at Evotec) discusses the challenges of studying GPCRs and how WAVEsystem enabled confident measurements under these difficult conditions.
According to Dr. Fabini, “having a fast and sensitive technology like GCI opens up new possibilities when it comes to quantifying low-signal, weak binding events with confidence.”
Evotec is a life science company committed to advancing drug discovery and development through collaborations with biotech, pharma, academia, and government agencies.
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