| 00:00:00 | Zetasizer Nano Applications |
| 00:00:08 | Outline |
| 00:00:25 | Light Scattering |
| 00:00:47 | Dynamic Light Scattering (DLS) |
| 00:00:58 | Electrophoretic Light Scattering (ELS) |
| 00:01:15 | What’s In An Expiration Date? |
| 00:01:34 | Formulation Time Trials |
| 00:01:48 | Emulsion Shelf Life |
| 00:01:56 | Protein Stability |
| 00:02:15 | Z Average & Quality Control |
| 00:02:30 | Formulation Stability - Steric Effects |
| 00:02:41 | Formulation Stability - Electrostatics |
| 00:02:57 | Zeta Potential |
| 00:03:13 | Factors Influencing The Zeta Potential |
| 00:03:23 | pH Effects |
| 00:03:42 | Salt Effects |
| 00:04:01 | Additive Effects |
| 00:04:14 | Zeta Potential - Shelf Life Correlation |
| 00:04:29 | Monitoring & Predicting Stability |
| 00:05:01 | Using TM As A Stability Predictor |
| 00:05:20 | Protein TM And Shelf Life Correlation |
| 00:05:31 | Blood Substitute Stability |
| 00:05:41 | Zetasizer Technical Specifications |
| 00:05:56 | Why Malvern Instruments? |
The Zetasizer Nano measures size using dynamic light scattering to monitor time dependent aggregation of protein formulations, and zeta potential to characterize surface properties, that can be linked with stability and shelf life