Morphologi 4 user guide (English)
Version number: MAN0595-04-EN
See the current Morphologi range . Learn more
Learn moreMorphologi 4 provides detailed morphological descriptions of particulate samples through static image analysis, enabling a greater understanding of both sample and process. It can equally be used as an R&D tool to investigate challenging applications and in automated QC analysis where generation of robust, user-independent results and validation are required.
Version number: MAN0595-04-EN
Version number: MAN0594-05-EN
Version number: MAN0609-03-EN
Version number: MAN0603-03-EN
Version number: MAN0594-03-DE
Version number: MAN0603-02-FR-00
Version number: MAN0595-03-FR-00
Version number: MAN0594-03-FR-00
Reverting to a previous driver version and improving the robustness of the image capture code and ability to restart an unresponsive camera to maintain ESD compliance.
Version 10.32 fixes 2 critical bugs, the audit trail files are now protected from accidental modification and manual light
setting measurements which were prevented by v10.31 can be run again.
This release improves the Installation Qualification (IQ) process with new Performance Verification (PV) and system
check reports for Morphological and ID components. Stability and security have also been
improved with new camera drivers and restrictions on custom calculation functionality.
Improved spectral performance
Appropriate dispersion of the individual particles and agglomerates within a sample leads to robust and reliable results. Good spatial separation and representative sampling of the particles is required. To achieve this, a number of dispersion options are available with the Morphologi 4.
Easy, reproducible, automated sample dispersion
Morphologi 4 comes with an integrated dry powder dispersion unit. It enables simple, reproducible preparation of dry powder samples. A precise amount of sample is dispersed automatically using a unique compressed air dispersion mechanism controlled from within the software, for reproducible dispersions every time.
Optional accessories – for analysis of particles in suspension
A range of instrument accessories supports preparation of samples on microscope slides, in wet suspensions or on filters, extending the capability of the Morphologi 4 beyond the characterization of dry sample dispersions. Each accessory fits directly into the automated stage area and is easily selectable in the Morphologi software.
The thin-path wet cell is designed for both morphological and chemical characterization of up to 100 μL of sample. It is ideal for applications such as the identification of subvisible particles in therapeutics (described by guidance in USP <787> and USP <788>), especially when a traditional membrane filtering approach may risk changing particles of interest, such as protein aggregates.
The wet dispersion cell allows between 2 ml and 6 ml of sample to be analyzed. This is particularly useful for characterizing larger particles or where volumetric particle count is important.
‘Sandwiching’ a few μL of a suspension of smaller particles between a microscope slide and a cover slip is a traditional method of sample preparation for microscopy. Samples are presented in this form to the Morphologi G3-ID using either the 2-slide or 4-slide holder. Slides suitable for chemical identification applications are available.
The twin 35 mm petri dish holder provides an alternative means of measuring suspended particles that may be at risk of being deformed when dispersed into a cell.
Fused silica filters are designed to enable the analysis of filtered samples containing low-contrast particles, such as protein aggregates or contaminant particles. The fused silica filters are housed in a support for ease of handling, and are presented to the Morphologi in the fused silica holder, which can hold up to 2 filters.
Protect your investment and ensure optimized performance at all times with Malvern Panalytical's service plans.
When you purchase a Malvern Panalytical product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern Panalytical will provide the support for your business.
For laboratories where maximizing instrument up-time is critical to its daily performance. Our highest level of response and the 'all inclusive' price plan takes care of those unexpected repair bills should the unfortunate occur.
Enhance your laboratory productivity by maintaining instrument efficiency. Still receive that priority response, combined with specialist technical and software support, we'll keep your instrument performance on track to deliver.
For laboratories looking to optimize instrument performance, regular preventative maintenance is essential.
Platinum Plan | Gold Plan | Bronze Visit | |
---|---|---|---|
Annual PM/PV Test | yes | yes | no |
Telephone / Email Support | yes | yes | no |
Priority Response | yes | yes | no |
Emergency Breakdown visits* | yes | yes | no |
Parts Included | yes | no | no |
Technical & Software Support | yes | yes | yes |
IQ/OQ (Pharma)*** | yes | yes | yes |
*including labour & travel costs ***available at an additional cost