Particle characterization is the process of measuring and analyzing the physical and chemical properties of particles, including their size, shape, surface area, and chemical composition.
This analysis is crucial for understanding the behavior and performance of particles in various applications.
Importance in Various Fields
- Pharmaceuticals: Particle characterization ensures drug consistency, efficacy, and safety. Accurate measurement of particle size and distribution can influence the dissolution rate, bioavailability, and stability of pharmaceutical products.
- Materials Science: In materials science, particle characterization helps in enhancing the properties of materials, such as strength, durability, and reactivity. It is essential for the development of new materials and the improvement of existing ones.
- Environmental Monitoring: Particle characterization plays a critical role in assessing pollution levels and understanding the impact of particulate matter on health and the environment. Accurate particle analysis can inform regulatory standards and pollution control measures.
Materials science and engineering
Environmental monitoring & analysis
Particle characterization techniques
Dynamic Light Scattering (DLS)
Dynamic Light Scattering (DLS) is a technique used to measure the size distribution of small particles in suspension or polymers in solution. It works by analyzing the fluctuations in light scattering caused by the Brownian motion of particles. DLS is widely used in pharmaceuticals and materials science for characterizing nanoparticles, proteins, and other colloidal systems.
The Zetasizer Advance range by Malvern Panalytical offers high-performance instruments for DLS measurements, providing accurate particle size analysis for research and quality control. For over 40 years, Malvern Panalytical has been an innovator in DLS systems and is the trusted market leader in this space. The Zetasizer Advance range builds on this proud history, offering high sensitivity, ease of use, and actionable data analytics to help you further your product development and research with confidence.
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Dynamic Light Scattering (DLS)
Zetasizer Advance Range
Innovative Solutions Utilized during AAV Characterization
Dynamic Light Scattering method development using the Zetasizer Advance Series
Laser diffraction
Laser Diffraction is a widely used technique for measuring particle size distributions. It works by detecting the pattern of light scattered by particles when illuminated by a laser beam. This technique is applicable in industries such as pharmaceuticals, food and beverage, and materials science for quality control and research.
The Mastersizer 3000+ range by Malvern Panalytical provides accurate and repeatable particle size distributions using laser diffraction, suitable for a variety of industrial and research applications.
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Laser Diffraction (LD)
Mastersizer range
Battery manufacturing: Reliable, adaptable particle sizing using the Mastersizer 3000+
Small-molecule drug substances: Regulation-compliant, reliable particle sizing using the Mastersizer 3000+
Nanoparticle Tracking Analysis
Nanoparticle Tracking Analysis tracks the Brownian motion of individual particles in suspension to measure their size and concentration. This technique is particularly useful for analyzing nanoparticles in complex fluids. Nanoparticle tracking analysis is widely used in nanotechnology, life sciences, and environmental monitoring.
The Nanosight Pro by Malvern Panalytical offers high-resolution size distribution and concentration measurements of nanoparticles using PTA technology.
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Nanoparticle Tracking Analysis (NTA)
NanoSight Pro
Characterizing the size and concentration of liposomes using NanoSight Pro
Utilization and Characterization of Biologically Sourced Nanoparticles: Exosomes and Viral particles
Best Practices for Nanoparticle Tracking Analysis
Zeta Potential Analysis
Zeta Potential Analysis measures the surface charge of particles in suspension, which affects their stability and interactions. This technique is crucial for understanding and controlling colloidal stability in pharmaceuticals, cosmetics, and other industries.
The Zetasizer Advance range by Malvern Panalytical includes instruments that provide both DLS and zeta potential measurements, offering comprehensive particle characterization capabilities.
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Zeta potential
Zetasizer Advance Range
Using zeta potential for the surface characterization of viral and lipid-based vectors
Zeta potential method development
Malvern Panalytical instruments for particle characterization
Mastersizer range
The smartest way to measure particle size
Mastersizer 3000+ range
The Mastersizer 3000+ range uses laser diffraction to measure particle size distribution. It offers a broad measurement range from submicron to millimeter sizes, with rapid and reliable results.
- Applications: Suitable for a wide variety of industries, including pharmaceuticals, chemicals, and food and beverage
- Benefits: Provides high-resolution particle size analysis, easy-to-use software, and robust data for quality control and research
Zetasizer Advance Range
Light Scattering for every application
Zetasizer Advance range
The Zetasizer Advance range utilizes dynamic light scattering (DLS) for particle size and particle concentration analysis and electrophoretic light scattering (ELS) for zeta potential measurement. It offers precise and reliable measurements for nanoparticles, colloids, and proteins.
- Applications: Used in pharmaceuticals, cosmetics, and nanomaterials research
- Benefits: Delivers high sensitivity and accuracy, user-friendly interface, and versatility for multiple types of analyses
Morphologi range
Automated imaging for advanced particle characterization
Morphologi range
The Morphologi range provides automated imaging for detailed particle size and shape analysis. It offers high-resolution imaging and comprehensive morphological data.
- Applications: Ideal for quality control in pharmaceuticals, materials science, and environmental monitoring
- Benefits: Offers detailed morphological analysis, high throughput, and easy integration into existing workflows
Spraytec
Spray particle and spray droplet size measurement
Spraytec
Spraytec uses laser diffraction to measure spray droplet and particle size distributions in real-time. It is designed to handle a wide range of spray types and conditions.
- Applications: Used in pharmaceuticals, agriculture, and consumer products for spray characterization
- Benefits: Provides real-time data, robust and flexible design, and high accuracy in diverse spray environments
NanoSight Pro
Characterizing Nano- and Biomaterials has never been so quick, easy, and ac...
Nanosight Pro
The Nanosight Pro employs nanoparticle tracking analysis (NTA) to measure particle size distribution and concentration. It offers high-resolution tracking and visualization of nanoparticles.
- Applications: Widely used in nanotechnology, life sciences, and environmental monitoring
- Benefits: Provides high-resolution size distribution, concentration measurements, and real-time visualization of particle behavior
Insitec range
Robust, reliable, real-time particle sizing
Insitec range
The Insitec range offers on-line particle size analyzers for real-time process monitoring and control. It uses laser diffraction to provide continuous measurement of particle size distributions.
- Applications: Ideal for the manufacturing industry, including pharmaceuticals, chemicals, and food processing
- Benefits: Enables real-time process optimization, improves product consistency, and reduces waste with continuous monitoring