Ensuring Consistent Viral Product Quality Using Advanced Analytics to Characterize Viral Particle Count and Infectious Titer

Viruses are complex molecules used in the research, development, and manufacturing of a wide range of products including live virus vaccines, oncolytic viruses, and viral vectors. This complexity necessitates the use of appropriate analytical methods to fully characterize these products and processes to ensure quality and consistency. The generation and stability of viruses can be profoundly influenced by various environmental conditions during the production and purification process, including temperature fluctuations, pH changes, oxidative stress, and osmotic pressure alterations. The potential impact of these processing parameters, highlights the importance for an accurate assessment of viral particle counts and infectious titer throughout research, development and manufacturing.

In this webinar, attendees will learn how to characterize viral product quality using the Nanosight Pro to measure viral particle count and the LumaCyte Radiance® instrument to measure infectious viral titer as well as how these parameters can change throughout the development and manufacturing process. Scientists, engineers, and technical experts in the R&D, process development, analytical development, formulations, and quality control areas would be interested in attending to learn how to use these advanced technologies to improve their manufacturing process.