Improving the development efficiency of drug-encapsulating nanoparticles using microfluidics and Multi-Angle Dynamic Light Scattering (MADLS)

Dolomite Microfluidics specializes in the production of high-performance nano- and microparticles which are precision-engineered for advanced functionality and encapsulation. These materials have unique properties determined by their size, shape and architecture which enable them to be used as specialized research tools within biomedicine, diagnostic imaging and industrial catalysis. At Dolomite Microfluidics, state-of-the-art automated continuous flow processing and droplet microfluidics are used to ensure very monodisperse particles with high batch-to-batch consistency.

This webinar explores the combined use of the Malvern Panalytical Zetasizer Ultra and the Dolomite Microfluidics system to generate drug-encapsulating nanoparticles with improved monodispersity and higher encapsulation efficiency, and with better reproducibility than a batch system. The Dolomite Microfluidics system enables very precise control of the size and composition of the nanoparticles. Applying the Zetasizer Ultra to characterize the nanoparticles enables faster and less expensive development of the microfluidic methodologies, due to the instrument’s unique Multi Angle DLS (MADLS) capabilities. MADLS provides the speed and size resolution needed to identify distinct populations, allowing quick iteration and consistent production of nanoparticles of a very high quality.